European Journal of Biomedical and Pharmaceutical Sciences

HAZARD RATIO PREDICTION | DIABETES MELLITUS AND BMI RELATIONSHIP: STUDY IN A TERTIARY CARE HOSPITAL OF PAKISTAN

Zulfiqar Khosa*, Mukhtar Mehboob, Muhammad Zubair and Sania Murad

ABSTRACT

Objective: This designed study established the outcomes of raised BMI on diabetes mellitus type 2 beginning and its associated complications among Pakistani urban community. Methods: This study was conducted in Mohtarma Benazir Bhutto Hospital Quetta. The data obtained from 250 individuals from March 2016 to September 2016. A cox proportional hazard model was used to judge the consequences of elevated BMI at the diagnosis of diabetes mellitus. Grouping was made to differentiate BMI categories for elevation of BMI and its effects on progress of diabetes. Results: Different hazard ratio pattern in risk was observed for various classes diabetes mellitus (HR=1.21 to HR=2.41), Insulin dependent (HR=1.67 to HR=3.47), non diabetics (HR=1.24 to HR=2.89), employed (HR=1.32 to HR=2.99), unemployed (HR=1.12 to HR=3.23), with education (HR=1.43 to HR=1.98), smoking (HR=1.59 to HR=2.66), alcoholics (HR=1.3 to HR=2.99), hypertension (HR=1.77 to HR=3.70), married (HR=0.99 to HR=2.88) and unmarried (HR=1.17 to HR=1.89). Increased risks of developing diabetes mellitus manifested in the BMI >40. Least risks to develop DM found in unmarried individuals. Conclusions: Amongst diagnosed diabetes mellitus persons, increased body mass index BMI were linked with consistently greater hazard of worse effects. Yet moderately raised BMI is linked with augmented hazards of developing diabetes mellitus. Greater hazards noted in hypertensive group and lower level risks observed in unmarried individuals.

Keywords: This designed study non diabetics unmarried individuals.