European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON RELATIONSHIP BETWEEN LABORATORY PARAMETERS AND DEGREE OF POISONING IN A TERTIARY CARE HOSPITAL

Dr. Ebin A.K., Dr. Rahna Raheem, Dr. Varsha K.M., Dr. Eby Mathew*, Dr. Sheba Reji, Dr. Basavanna P.L.

ABSTRACT

Introduction: Acute poisoning is one of medical emergency conditions in all hospitals.[1] Laboratory parameters are important in providing adequate treatment for intoxicated patients. In this study, we aimed to analyze the laboratory parameters in a different type of poisoning and how it helps in identifying the condition of the patients. We have used the Glasgow Coma Scale (GCS) for assessing the patient’s conscious level. Methods: We selected 204 study population for our study during the period of September 2018- February 2019. The collected data reviewed and recorded in a designed data collecting form. Results: Out of 204 patients 66% were males and most cases detected in the age group of 25-34years. We found an abnormality in the mean values of Pulse Rate (PR), Respiratory Rate (RR), White Blood Cells (WBC), Random Blood Glucose (RBG), Alanine Phosphatase (ALT), Aspartate Phosphatase (AST) and Pseudo-cholinesterase level. There was a significant variation in laboratory parameters when relating to GCS. PR, RR, WBC, neutrophils, RBG, serum urea, serum Creatinine, and ALT increased gradually with a decrease in GCS scores. Only SpO2, lymphocytes, RBC and pseudo-cholinesterase declined with a decrease in GCS score. There were no significant variations among other parameters. Stomach wash was the initial treatment given for all type of poisoning except in the case of corrosive substances poisoning. Conclusion: We concluded our study by pointing out a significant variation in laboratory parameters when it was related to with the consciousness level of patient by using a severity scale.

Keywords: laboratory parameters, Glasgow coma scale.