European Journal of Biomedical and Pharmaceutical Sciences

CONJUNCTIVAL AUTOGRAFT PLUS TOPICAL AVASTIN: ACCOMPANIMENT IN PTERYGIUM TREATMENT

Dr. Sanjoy Chowdhury*, Dr. Madhumita Srivastava and Dr. Nilanjan Chowdhury

ABSTRACT

Pterygium results when there is aberrant wound healing characterised by centripetal growth of limbal epithelial cells followed by squamous metaplasia giving rise to pterygial epithelium with goblet cell hyperplasia. A prospective, randomized, comparative, interventional study was conducted to treat pterygium. This study was done with an aim to examine the efficacy of post-operative topical Bevacizumab drops in preventing recurrence of pterygium excision with autologous graft placement. Results show that low-dose topical Avastin and Conjunctival autograft are more effective as adjunctive treatment after excision of primary pterygia.

Keywords: Pterygium, Vascular Endothelial Growth Factor, Conjunctival in situ autografting and Bevacizumab.