PHARMACOGNOSTIC, PHYSICOCHEMICAL, AND PHYTOCHEMICAL ANALYSIS OF HARIDRADI CHURNA
Shraddha Chaudhary*, Dr. D. B. Vaghela and C. R. Harisha
ABSTRACT
Background: Standardization of herbal medicines is essential to establish its identity, purity, quality, safety, and efficacy. This study reports on standardization of Haridradi Churna an Anubhuta Yoga for management of Tonsillitis. Objective: This study aimed to prepare the Haridradi Churna using authentic herb and establishing pharmacognostical, physicochemical and phytochemical standards for the formulation. Materials and Methods: Haridradi Churna was prepared and the prepared formulation was evaluated for pharmacognostical, physicochemical, and phytochemical parameters using guidelines of the World Health Organization and Pharmacopoeial Laboratory for Indian Medicines for quality control of herbal drugs. Results: Haridradi Churna was obtained as a coarse, fine, yellow, aromatic powder with astrigent taste. Water soluble extractive value of 46.05% and methanol solule extractive value of 32.40% were obtained in hydroalcoholic and petroleum ether, respectively. Ash values 42.54% acid insoluble ash 1.47%,loss on drying 10.54%, pH value (by pH paper) 9, were observed. No microbial load was detected in the formulation. Microscopic studies revealed the presence of various characteristic entities. Preliminary phytochemical screening confirms the presence of alkaloids, flavonoids, glycosides, fatty acids, terpenoids, sterols, tannins, proteins, and phenolic compounds. HPTLC study showed 05 spots at 254 nm with Rf values and 03 spots at 366 nm with Rf values. Conclusion: The various pharmacognostical, physicochemical, and phytochemical standards will help in quality control/quality assurance and maintaining batch to batch consistency in herbal drug industries so that maximum therapeutic efficacy can be achieved.
Keywords: Pharmacognostic, physicochemical, phytochemical, Haridradi Churna.
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