European Journal of Biomedical and Pharmaceutical Sciences

EOSINOPHILIA IN HOSPITALIZED PATIENTS, A RETROSPECTIVE STUDY

Rame Khasawneh, MD. Mohammad Maaytah, MD. Nagah Al Drous, MD. Ahmad Bani Salameh, MD. Bayan Alzgoul, MD. Mansour Hyari, MD. Nabeeha Abbasi, MD. Hala Alsoukni, MD. Asim Momani, MD.*

ABSTRACT

Background: Eosinophilia is associated with a large number of diseases and clinical conditions, but there is no information about the clinical characteristics of patients who are hospitalized due to this abnormality. The aim of this study is to determine the clinical profile and most informative diagnostic tests in patients hospitalized in a tertiary hospital with the finding of eosinophilia. Methods: This is a retrospective study that was done in the time period between January, 2015 till June, 2015 as a collaborative effort between Princess Iman Center for Laboratory Sciences and Research and the Internal Medicine Department/ King Hussein Medical City. Data was retrieved from the medical records of patients who were hospitalized with the finding of eosinophilia. All relevant data including clinical findings, laboratory tests, and imaging studies were analyzed. Results: A total of 130 patients were included in the study; (65 males and 60 females, with an age range between 26 and 60 years). The blood eosinophil absolute count was 2500-5600/μl (mean±SD) and this in the majority of cases persisted for a few months. The causes of the eosinophilia were:  Asthma or other atopic disease in 28patients (21.5%),  Pneumonia in 20 patients (15.4%),  Neoplastic diseases in 18 patients (13.8%),  Infections in12 patients (9.2%),  Skin diseases in 6 patients (4.6%),  Allergic drug reaction 5 patients (3.8%),  Hypereosinophilic syndrome in 1patient (0.77%),  And the cause was unknown in 40 patients (30.8%). Conclusion: Guidelines are needed for the investigation of patients hospitalized with eosinophilia, including the level of the eosinophilia associated with specific diseases and the most information yielding diagnostic tests.

Keywords: Eosinophilia, Allergy, Pneumonia, Neoplastic, Hypereosinophilic syndrome.