A NEW ANTHRAQUINONE FROM MORINDA LUCIDA BENTH
Bi Koffi François Prévost Kouamé*, Aka Faustin Kabran, Ballo Daouda, Doumadé Zon, Nakognon Tuo Kouassi Awa, Gbè Gondo Didier Diomandé, Sagne Jacques Akpa, Landry Kablan, Gustave Bedi, Denis Loquet, Illa Tea, Richard Robins, Ané Adjou and Felix Zanahi Tonzibo
ABSTRACT
Morinda lucida (Rubiaceae) is a known medicinal plant used in traditional medicine in West Africa for the treatment of diseases and infections. The purpose of the present study was to investigate the chemical constituents of the stem barks of M. lucida from Côte d’Ivoire. The isolation of the compounds was carried out by a combination of silica gel column, sephadex gel filtration chromatography, preparative normal phase TLC and reverse-phase-C18 preparative TLC. The chemical structures were elucidated with the help of MS, 1D, 2D - 1H and 13C NMR spectroscopic analysis, as well as the comparison of spectra data with that reported in the literature. The present phytochemical investigation led to the isolation and characterization of one new anthraquinone, 1,5,15-trimethylmorindol (8) together with seven known anthraquinones, 3-hydroxy-2-hydroxymethyl-anthraquinone (1), damnacanthol (2), soranjidiol (3), rubiadin (4), damnacanthol-l-methyl ether (5), lucidin (6) and alizarin-1-methyl ether (7) from the stem barks of M. lucida.
Keywords: Morinda lucida, Rubiaceae, stem bark, anthraquinone.
[Full Text Article]
[Download Certificate]
Impact Factor : 8.181 
