European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW ON MODES OF VACCINE DELIVERY SYSTEMS IN PHARMACEUTICAL INDUSTRIES

Aarthi B., Punnya P. Nair, Thaslim A. R., Prabhu N.*

ABSTRACT

Vaccines are developed to prevent the diseases by stimulating the immune response to act against the antigen. Many pandemic diseases can be prevented through vaccination. Vaccination can be done through different modes like parenteral, oral and intranasal. Vaccine technology is developing day to day to increase the efficiency of vaccination and to develop safe vaccines. Vaccines can be delivered through vehicles that can carry the antigen. Vaccine delivery vehicles play an important role in administering vaccines because certain vehicles are suitable and effective for certain types of antigens. Nanoparticles, organic compounds, polymeric materials can be used as vaccine delivery systems and can act also adjuvants. Plant-based oral vaccines or edible vaccines attracts scientists as it is cost-effective and can be easily administered. Many factors will influence the vaccine delivery. The environment where the vaccine is delivered should stabilize antigens and the antigens should release for immune response. Finally, vaccination is important and the mode of delivery will determine the effectiveness of vaccination.

Keywords: Mode of vaccination, oral vaccination, edible vaccines, vaccine delivery vehicles.