European Journal of Biomedical and Pharmaceutical Sciences

PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF HYDROALCOHOLIC FRUIT EXTRACT OF CUCUMIS DIPSACEUS

Nadhiya R.*, Sengottuvel T., Gopalasatheeskumar K. and Ariharasivakumar G.

ABSTRACT

The antioxidants are vital in life. Because, most of the diseases are caused by free radicals which are scavenged by the antioxidants. Naturally herbals has the antioxidants role with the phytochemicals such as flavonoids, vitamin C, Vitamin E etc., So that, current research is focused on study of antioxidant activity of herbal. Cucumis dipsaceus Ehrenb is annual climbing herb, belong to genus Cucumis L., family Cucurbitaceae. Commonly, Hydroalcohol is a suitable solvent for successive extraction of polar and non polar phytoconstituents. Many of the hydroalcoholic plant extract have potent antioxidant activity, since there is no evidence for Cucumis dipsaceus. Therefore current research is focused on antioxidant activity of hydroalcoholic fruit extract of Cucumis dipsaceus (HAFEC). The antioxidant activity was evaluated using DPPH and ABTS radical scavenging assays. The results of current research revealed that HAFEC has potent antioxidant activity which produced similar effect to standard quercetin. Results concluded that, the antioxidant activity of HAFEC may be due to the presence of phytoconstituents such as flavonoids, triterpenoids, catechin etc., the future direction of this study is to perform in vivo studies and finding of molecular mechanism.

Keywords: Cucurbitaceae, In vitro, DPPH, ABTS, flavonoid.