European Journal of Biomedical and Pharmaceutical Sciences

LABORATORY DIAGNOSTIC LINK TO POLYCYSTIC OVARY SYNDROME – AN UPDATE

Rajeswari S, Gowri Meena S and Swaminathan S*

ABSTRACT

Polycystic ovary syndrome (PCOS) is a common endocrine disorder among women of reproductive age, occurring in approximately among 15% of women in India and it is the leading cause of infertility. Hormonal imbalance has been identified as the leading cause for PCOS. Calcium, Magnesium & Vitamin D deficiencies along with insulin resistance have been implicated as causes of PCOS and their supplementation has been highlighted in many studies. Weight loss management improves follicle maturation, menstrual regularity and improvement of hyperandrogenism. The high prevalence of 25(OH)D deficiency in PCOS is a common findings and is a real alarm for public health care system. Women with PCOS had the highest odds of diabetes and an increased risk of cardiovascular disease. Hyperprolactinemia is also frequently reported in PCOS. The rate of patients with elevated LH levels and LH/FSH ratio were significantly higher in the late phase than in the early phase among PCOS. This review article present the research findings related to laboratory diagnosis with special emphasis on the role of calcium, Vitamin D, magnesium, prolactin, LH and FSH.

Keywords: PCOS, Calcium, Vitamin D, LH, FSH.