European Journal of Biomedical and Pharmaceutical Sciences

PROPERTIES AND UTILITY OF MADHYAMA RASNADI DECOCTION: A MULTIHERBAL FORMULA

RLDS Ranasinghe* and RHSK De Silva

ABSTRACT

Ayurveda physicians commonly use Madhyama Rasnadi decoction in the management of inflammatory conditions. This exploratory study aims to justify the actions and usage of Madhyma Rasnadi decoction by analysing its Ayurveda pharmacodynamic properties, phytochemical content and bioactivities and to find out the possible other indications. Data were collected from authentic Ayurveda texts and electronic sources and analysed into percentages according to their Ayurveda pharmacodynamics properties. Variations have been identified in terms of preparation method and the dosage of the decoction. The ingredients of Madhyama Rasnadi decoction predominantly have Ayurveda pharmacodynamic properties such as Tikta Rasa, Laghu Guna, Ushna Virya and Katu Vipaka. Almost all the ingredients possess Deepana, Pachana, Rochana, Rakta Shodhana, Vatanulomana, Shula Prashamana and Mutrala properties. The ingredients comprise various phytochemicals such as flavonoids, tannins, phenols, alkaloids and glycosides. Analgesic, anti-inflammatory, antioxidant, hypoglycemic, antimicrobial, hepatoprotective, immunomodulatory and anti-arthritic activities of the individual ingredients have been scientifically proven. It can be justified that due to its properties Madhyama Rasnadi decoction can be effectively used to manage inflammatory conditions like rheumatoid arthritis and also to manage degenerative and oxidative stress-related diseases. A future study is planned to analyse the variations of the phytochemical content according to the preparation method.

Keywords: Madhyama Rasnadi decoction; Ayurveda Pharmacodynamic properties; Antioxidants; Phytochemicals; Bioactivities.