European Journal of Biomedical and Pharmaceutical Sciences

CORRELATION OF CORONARY ARTERY CALCIUM AND INVASIVE CORONARY ANGIOGRAPHICALLY IN PATIENTS WITH ATYPICAL ANGINA PECTORIS (CACICA - TRIAL)

Majed Elshenat, MD*, Mohammed Balosha#, Mohammed Habib, MD, PhD*

ABSTRACT

Objectives: This study correlated the multi - detector computed tomography (MDCT) calcium scores with the results of coronary angiography in diabatic and/or hypertensive patients with atypical angina pectoris in order to assess its value to predict or exclude significant coronary artery disease (CAD). Background: Muti-detector computed tomography is a sensitive method to detect coronary calcium. However, it is unclear whether it may play a role as a filter before invasive procedures in patients with atypical angina pectoris. METHODS: A total of 150 patients (116 men and 34 women) with diabetic and/or hypertension for at least 5 years and atypical angina pectoris from a single center were included in our study. patients underwent calcium screening with MDCT and have calcium score more than 100 , then all patient underwent invasive coronary angiography. Results: The Mean age was 62±5.7 and 77.3% were male, 78% of men and 88.2% of women revealed significant coronary stenoses (> 50% lumen narrowing of left main trunk stenosis and > 70% stenosis of any epicardial coronary artery). Significant correlation between calcium scoring and significant coronary artery stenosis was seen (P: 0001). A 70% were DM, 90% were hypertensive and 61.3% were HTN and DM. The LAD artery was the most stenotic artery by 53.3% followed by RCA (37.3%) and finally LCX (30.7%). Number of significant artery stenosis: one significant coronary artery was 42% followed by two significant CAD (26.7%), while 9.3% included three-vessel disease. The significant coronary artery diseases was increased with age (P: 0003). Conclusions: Coronary calcium proved to have good diagnostic performance for significant coronary artery stenosis in patient with atypical angina pectoris.

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