Abstract
SYNTHESIS AND ANTIBACTERIAL ACTIVITY STUDYS OF 8, 9-DI HYDRO 7H BENZO 1,2,4-OXADIAZOL-3-YL]-4-METHYL-2H-CHROMEN-2-ONES

Dr. A.L.V Ramana Reddy*

ABSTRACT

Synthesis, spectral analysis and bioactivity of new coumarin derivatives are described in this paper. Eight new coumarin derivatives were synthesized in moderate to good yields by react with 4-carbonyl chloride via 1,2-dichloroethane and done by the conventional and micro wave irradiation. The structures of all the newly synthesized molecules were assigned by elemental analysis and spectral data. The synthesized compounds were screened for their antibacterial activities strains using Cup plate method.

Keywords: Antimicrobial activity, microwave irradiation, 1, 2-dichloroethane, PTSA.


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