Abstract
FORMULATION AND EVALUATION OF PRAZOSIN HYDROCHLORIDE BY USING NATURAL POLYMERS LIKE GELATIN AND CHITOSAN

Gopisetty Saran*, Rohith Sarswat, Ashok Kumar B. S., Sridhar S. M., Pradeep Kumar L.

ABSTRACT

The aim of this study was to formulate and evaluate microspheres as controlled release preparations of a highly water-insoluble drug, Prazosin HCL, using natural polymers, Chitoson and Gelatin materials. It is recently developed anti hypertensive drug used effectively in therapeutic practice. However, the Prazosin HCL has short half life and hence requires frequent administration. Therefore the possible way by which this can be overcome is formulating a controlled release formulation (CSR).

Keywords: Prazosin HCL, CSR.


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