Abstract
EVALUATION OF DIURETIC AND NATRIURETIC ACTIVITY OF ETHANOLIC EXTRACT OF BOERHAVIA DIFFUSA LINN ROOT IN ALBINO WISTAR RATS

Dr. Vijay Patel* and Rekha Gour

ABSTRACT

Boerhavia diffusa commonly known as punarnava is a perennial herbaceous plant belonging to family Nyctaginaceae. The medicinal value of this plant in the treatment of a large number of human ailments is mentioned in Ayurveda, Charaka Samhita, and Sushruta Samhita. The aim of present study was to evaluate diuretic and natriuretic activity of ethanolic extracts of Boerhavia diffusa root in albino wistar rats. The results of preliminary phytochemical evaluation revealed the presence of Alkaloids, Glycosides, Flavonoids, Proteins, amino acids, Carbohydrates, Steroids, Fats and oils, Tannins and phenols. In acute oral toxicity, animals didn‟t show any visible signs of morbidity and mortality. Four groups of Albino wistar rats were used to evaluate diuretic activity of ethanolic extract of roots of Boerhavia diffusa by using Lipschitz test model. Oral administration of Boerhavia diffusa at doses 100 mg/kg and 200 mg/kg produced a significant (P< 0.01) increase in the urine volume when compared to control and standard. Determination of urinary electrolyte concentration in urine was done by using a flame photometer. It has revealed that ethanolic extract of Boerhavia diffusa roots was effective in increasing urinary sodium concentration. The results were analyzed by One Way Analysis of Variance (ANOVA). Thus, in conclusion the Boerhavia diffusa has a significant diuretic and natriuretic action in rats.

Keywords: Diuretic, Natriuretic activity, Ethanolic extract, Lipschitz test, Boerhaavia diffusa, Furosemide.


[Full Text Article]   [Download Certificate]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: JULY ISSUE PUBLISHED

    JULY 2024 Issue has been successfully launched on 1 JULY 2024.

  • EJBPS New Impact Factor

    EJBPS Impact Factor has been Increased to 7.482 for Year 2024.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT