European Journal of Biomedical and Pharmaceutical Sciences

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL INVESTIGATION OF ALLIUM SATIVUM

Monali Dumore, Ashwini Chandewar*, Ankita Gaidhane, Bharti Ambadkar and Omkar More

ABSTRACT

Natural products have been an integral part of ancient traditional medicine system. the objective of the study was investigate the phytochemical constituent and proximate composition of garlic (A.sativum) extracts. The phytochemical screening of the garlic for various phytochemical constituents was conducted using laboratory method. The proximate and mineral composition was determined by using standard method. the qualitative phytochemical screening of the Allium sativum aqueous and ethanol extract indicate the presence of the alkaloids, terpenoids, flavonoids, steroids, saponin, tannins and phenol. The qualitative proximate composition of the bulb in g/100g showed the extract contain carbohydrate, protein, fats. The chemical analysis revealed that the l sulphated ash value of the compound was found to be 0.20%, the total ash value of the compound was found to be 3.20% and the loss on drying showing the 6% which resemblance of the standard value of that compound itself. The alcoholic extract of the compound shows the zone of inhibition while comparing with the streptomycin as the standard it showing 10mg/ml, it was shown approximately 13mm it shows Allium sativum having antimicrobial activity.

Keywords: Allium sativum, alkaloids, terpenoids, flavonoids, steroids, saponin, tannins and phenol.