Abstract
EVALUATION OF ANTI INFLAMMATORY ACTIVITY OF THE SEEDS OF LUFFAACUTANGULA ROXB IN ANIMAL MODEL

Burhan Ali*, Biswaranjan Ray and Bipin Bihari Panda

ABSTRACT

Objective: To evaluate the acute anti-inflammatory properties of different doses of ethanolic extracts of leaf of Luffa acutangula Roxb on carrageenan induced paw oedema of rats. Material and methods: The three doses of Luffa acutangula Roxb was extracted by using Ethanol. The anti-inflammatory profile of these extracts was investigated on the basis of paw edema induced by carrageenan. The animals were divided into 5 groups of 6 animals each. Group I served as control. Group II served as standard and Administered Aspirin. Group III and IV and V were treated orally with 50 mg/kg, 100 mg/kg and 200 mg/kg extract body weight respectively. Results: All the extracts showed considerable dose dependent activity. However ethanol extract 200mg/kg showed higher activity than other extracts. Conclusion: The different doses of leaf extract has anti inflammatory property. Further study needed to put the anti inflammatory Property in a precise way.

Keywords: Inflammation; Carrageenan; Paw edema.


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