European Journal of Biomedical and Pharmaceutical Sciences

SERUM ANTIOXIDANT MINERALS AND LIPID PROFILE STATUS AMONG GERIATRIC SUBJECTS

Wali U.*, Jelani I., Kakako S.L., Yanusa N.D. and Jabir M.Y.

ABSTRACT

Aging has been inevitable processes which occur overtime even in the absence of injury and thought to be characterized by oxidative stress and dyslipidaemia. A total of fifty (50) apparently healthy geriatric subjects were recruited in the study and serum malondialdehyde (MDA), copper, manganese, and zinc and lipid profile (total cholesterol, triacylglycerol, low density lipoprotein, high density lipoprotein, very low density lipoprotein and atherogenic index) were determined and the results compared to thirty (30) apparently young adults of socio and economic status using standard chemical method and atomic absorption spectrometry. The results indicated significant increase (P<0.05) in MDA, TC, TG, LDL-C, VLDL-C, AIX and decrease in copper, manganese and zinc in geriatrics when compared to those of young adults (control). The results further revealed that gender had no effect on antioxidant minerals and lipid profile but antioxidant minerals and lipid profile are age dependent.The results suggest that oxidative stress and dyslipidaemia could be attributing factors for aging.

Keywords: Oxidative stress, antioxidant minerals, lipid profile.