Abstract
CONTRADICTORY OPINION OF THE TERMINALIA CHEBULA LINN. -LITERATURE REVIEW

Dr. G. Sakthi*

ABSTRACT

Terminalia chebula is used as common and effective herb in traditional, Siddha & Ayurvedic medicine as Indian Medicine. In siddha medical system know as “Mother of Herb” is mentioned in manuscripts texts. In this research paper objected as enumerate the side effect or toxicity effect from Gall Nut or safe drug for all by searching the literatures in books and articles. Finally concluded by collected data results as; continuous drug period of intake for up to 3 months. And drug interactions reported as; Taking Terminalia along with diabetes medications might cause your blood sugar to go too low. In toxicity studies shows as; In the acute phase of the study, the safe dose was ≤5000 mg/kg for both extracts. In sub- acute phase, LD50 (95% CI) of Terminalia chebula extract 2754.436 (2438-3114) mg/kg. The highest dose of T. chebula extract induced few histopathological changes.

Keywords: Terminalia chebula, Drug Interaction, LD50.


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