European Journal of Biomedical and Pharmaceutical Sciences

BLOOD GLUCOSE LEVEL AND SERUM LIPID PROFILE OF WISTAR ALBINO RATS FED FOUR SPECIES OF LOCAL BEANS CONSUMED IN SOUTH-EAST, NIGERIA

Chukwuebuka Egbuna*, Jonathan C. Ifemeje, Andrew C. Nwaka, Michael Chinedu Olisah, Colin B. Lukong, Kingsley C. Patrick-Iwuanyanwu, Maryjane O. Ifemeje, Ikechukwu Harmony Iheukwumere, Iheukwumere C. M.

ABSTRACT

The glycemic and lipid profile status of Wistar albino rats fed four local species (C. Cajan, V. unguiculata subsp. sesquipedalis, P. vulgaris L „Red kidney‟, and P. vulgaris 'Black turtle‟) commonly consumed in South-east, Nigeria was examined. The experimental design comprises of 30 male Wistar rats distributed into 5 groups of 6 rats each. The effects of the beans on the glucose level suggests that the fasting blood glucose levels was higher in the group fed C. cajan while Red kidney group had the least fasting blood glucose levels. The effects of the beans on the lipid profile shows that P. vulgaris L „Red kidney‟ group had a higher serum cholesterol and HDL compared to the control while C. cajan had a higher LDL cholesterol than others while there was a general decrease in TG and VLDL across the group.

Keywords: Glucose level, lipid profile, cholesterol, triglycerides, beans, Wistar albino rats.