Abstract
PLASMID CURING POTENTIALS OF SOME MEDICINAL PLANTS AGAINST CITRATE NEGATIVE MOTILE SALMONELLA SPECIES

Iheukwumere I. H.*, Dimejesi S. A., Iheukwumere, C. M., Chude C. O., Egbe P. A., Nwaolisa C. N., Amutaigwe E. U., Nwakoby N. E., Egbuna C., Olisah M. C. and Ifemeje J. C.

ABSTRACT

Studies have shown that about 80% of multiple antibiotics genes, which possess threat to public health, are encoded in the plasmid. This study was undertaken to evaluate the plasmid curing potentials of Zingiber officinale (ZO), Ocimum gratissimum (GO) and Xylopia aethiopica (XA) extract against different strains of citrate-negative motile Salmonella species. Water samples were drawn from different water bodies closed to different hospitals, and screened for the presence of citrate-negative motile Salmonella species using pour plate technique. The isolates obtained were appropriately characterized. The resistance strains were detected by subjecting the isolates to antibiotic susceptibility test using disk diffusion technique. The plasmid curing potentials of the extract were ascertained by exposing the resistance isolates to different concentrations (1 %, 2 %, 3 %, 4 %, 5 %, 6 %, 7 % and 8 %) of the extracts, and subsequently to susceptibility test. The study revealed that 86 %, 71 %, 64 %, 55 % and 44 % of the citrate-negative motile Salmonella species (G, P, H, M and N) showed multiple antibiotics resistance to Ceporex (CEP), Ciprofloxacin (CPX), Ampicillin (PN), Septrin (STX) and Streptomycin (S). The multiple antibiotics resistance isolates were significantly (P<0.05) reduced by ZO (19 %, 12 %, 0 %, 0 %, 0 %), OG (33 %, 24 %, 7 %, 18 %, 0 %) and XA (43 %, 35 %, 29 %, 18 %, 11 %) extracts. From the above study, the extracts possessed pronounced plasmid curing potentials, of which ZO extract was most effective against the resistance strains.

Keywords: .


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • EJBPS: MARCH ISSUE PUBLISHED

    MARCH 2021 Issue has been successfully launched on 1 March 2021.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT