Abstract
ROLE OF MINERAL OIL IN NOVEL DRUG DELIVERY SYSTEM: AN OVERVIEW

Uday Prakash*, Dr. Atul Kumar Gangwar and Dr. Lalit Singh

ABSTRACT

Novel drug delivery systems are designed to achieve a continuous delivery of drugs at predictable and reproducible kinetics over an extended period of time in the circulation. Floating drug delivery system is the form of novel drug delivery system. That controls kinetic release rate of drug to a specific site for its pharmacological action. These are achieved by use of various oils including mineral oil. This delivery system prolongs the retention time of the drug in the stomach as compared to conventional dosage form. The present article highlights the use of mineral oil for the formulation of the floating drug delivery system especially with oil (mineral oil). The main goal of any drug delivery system is to achieve desired concentration of the drug in blood or tissue, which is therapeutically effective and non-toxic for a prolonged period. Oral delivery of drugs is by far the most preferable route of drug delivery due to the ease of administration, patient compliance and flexibility in formulation etc. From immediate release to site specific delivery, oral dosage forms have really progressed.

Keywords: Mineral oil, floating system, fermentation process.


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