SARS: A RATIONALE LITERATURE STUDY BASED ON ETIOLOGY, PATHOGENESIS AND MANAGEMENT
Dr. Rosemol Geo*
ABSTRACT
Severe acute respiratory syndrome (SARS) is a newfangled infectious disease instigated by a novel coronavirus that eventually result in deadly respiratory pathological complications. Owing to high spreading and death rate, SARS has progressed as a chief respiratory disease which may stumble upon ubiquitously around the world. The possible variability of the SARS-CoV genome may eventually give fresh SARS outbursts and several sections of the viral genomes open reading frames have been recognized which may provide to the intense harmfulness of the virus. The pathogenesis of SARS involves numerous mechanisms including both direct action on target cells as well as indirect action by means of the immune system. The utmost striking method to thwart novel epidemics of SARS is vaccination; nevertheless the expansion of vaccines is challenging owing to mislaid data on the part of immune system-virus relations and the highly probable mutability of the virus. Even though new infections are not reported currently, SARS leftovers as a foremost health hazard, as new epidemics may rise at any time. Consequently, advance experimental and clinical investigation is indispensable to halt the threat of this disease.
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