DENDRIMERS AND ITS APPLICATION: A REVIEW
Navneet Kumar Verma*, Asheesh Kumar Singh, Prem Chand Mall, Vikas Yadav, Rupali Jaiswal
ABSTRACT
A dendrimer is typically described as a macromolecule, which is characterized by its highly branched 3D structure that provides a high degree of surface functionality and adaptability. Dendrimers are a new class of polymeric materials. They are highly branched, monodisperse macromolecules. The structure of those materials features a great impact on their physical and chemical properties. As a results of their unique behaviour dendrimers are suitable for a good range of biomedical and industrial applications. The paper gives a concise review of dendrimers‟ physico-chemical properties and their possible use in various areas of research, technology and treatment. The bioactive agents can be easily encapsulated into the interior of the dendrimers or chemically attached that is conjugated or physically adsorbed onto the dendrimer surface, serving the desired properties of the carrier to the precise needs of the active material and its therapeutic applications. The review aims to stress on construction, characterisation, drug delivery and possible application of dendrimers in various areas of research, technology and treatment.
Keywords: Dendrimer, drug delivery, polyamidoamine dendrimer (PAMAM).
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