Abstract
EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF METHANOLIC EXTRACT OF BARK OF MANGIFERA INDICA AGAINST INH AND RIF INDUCED HEPATOTOXICITY IN RATS

A. Avinash*, B. Pravallika*, CH. Swathi*, K. Bhanu Prakash*, P. Swathi* and T. Bhanu Sri*

ABSTRACT

The present study was undertaken to evaluate the hepatoprotective activity of methanol extract of bark of Mangifera indica. It was evaluated in normal and Isoniazid (INH), Rifampicin (RIF) induced hepatotoxicity in rats. Liv.52 was used as a standard drug at a dose of 500mg/kg body weight given in oral route. Albino wistar rats with Isoniazid and Rifampicin induced hepatotoxicity were divided into 4 groups of 6 each. Hepatoprotective effect as two different doses 200 and 400 mg/kg body weight of methanolic extract of Mangifera indica would be investigated for 28 days to evaluate dose dependent activity. Effect of methanolic extract of Mangifera indica on Serum glutamate pyruvate transaminase, Serum glutamate oxaloacetic transaminase Alkaline phosphatase, total cholesterol, total bilirubin were estimated for 0th, 7th, 14th, 21st, 28th day and antioxidant parameters were checked on 28th day of the scarification.

Keywords: Mangifera indica, Albino –Wistar rats, Isoniazid, Rifampicin, Hepatoprotective activity.


[Full Text Article]   [Download Certificate]

Indexing

Indexing

Best Article Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: AUGUST ISSUE PUBLISHED

    AUGUST 2026 Issue has been successfully launched on 1 AUGUST 2026.

  • EJBPS: New Impact Factor 2026

    EJBPS Impact Factor has been Increased from  7.482 to 8.181 for Year 2026.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     
Google Scholar Index Copernicus Indian Science Publications Urlich's Periodicals Directory, Proquest, UK (In Process) Research Bible, Fuchu, Tokyo. JAPAN UDLedge Science Citation Index International Society for Research activity (ISRA) Scientific Indexing Services (SIS) InfoBase Index (In Process) SJIF Impact Factor Scholar Article Impact Factor, SAIF Universal Impact Factor CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Global Impact Factor (GIF) (0.377) IP Indexing (IP Value 3.77) Web of Science Group (Under Process) Directory of Research Journals Indexing Scope Database Academia Academia Doi-Digital Online Identifier Doi-Digital Online Identifier ISSN National Centre Zenodo Indexing International CODEN Service, USA

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT