Abstract
A REVIEW ON POSSIBLE PHARMACOLOGICAL OPTIONS AGAINST COVID-19

Dr. Ali Jaan, Dr. Muhammad Tayyeb, Dr. Farhan Khalid, Dr. Aftab Sharif, Dr. Dania Rahim Qureshi, Dr. Sarfaraz Ahmad, Dr. Zahoor Ahmed and Dr. Anum Awais*

ABSTRACT

The spread of Severe acute respiratory syndrome 2 (SARS-Cov-2), the causative agent of coronavirus disease (COVID-19) has become a public health emergency. The whole world is concerned about the pandemic of COVID-19 caused by widespread SARS-CoV-2 across the globe. This new disease and its causative virus have drawn its major global attention. The number of patients and death rates are continuously increasing. The research community and scientists have been conducting a major campaign to understand this new emergent disease and its epidemiology to uncover possible treatment regimens, discover effective therapeutic agents, and develop vaccines. Since SARS-CoV-2 is a newly discovered pathogen, no specific drugs have been identified or are currently available. Although, a few candidates have shown efficacy in vitro studies, as well as in pre-clinical studies, and some drugs have also shown efficacy in clinical practice, but not a single drug has proven effective in large clinical randomized clinical trials. This review summarizes the ongoing advances and clinical trials designing the therapeutics against COVID-19. The whole is waiting for the results of these clinical trials as a potential treatment against COVID-19.

Keywords: COVID-19, coronavirus, pharmacotherapy, treatment.


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