Abstract
DISCOVERY OF CURCUMIN: MIRACULOUS ACTIVITY AS ANTICANCER

Mona Patel* and Ojash Patel

ABSTRACT

Cancer is the second most life-threatening disease and one of the main public health problems worldwide now a day. Despite the great advances in cancer therapy, the incidence and mortality rates of cancer remain high. Therefore, the quest for more efficient and less toxic cancer treatment strategies is still at the forefront of current research. Curcumin, the active ingredient of the Curcuma longa plant, has received great attention over the past two decades as an anticancer agent, antioxidant and anti-inflammatory. Curcumin has been used either as a single agent or in combination with other agents. Modern science has shown that Curcumin modulates various signalling molecules, including inflammatory molecules, transcription factors, enzymes, protein kinase, protein reductase, carrier proteins, cell survival proteins, drug resistance proteins, adhesion molecules, growth factors, receptors, cell-cycle regulatory proteins, chemokine, DNA, RNA, and metal ions. In this review article, we discuss the discovery and key biological activities (specific as anticancer) of Curcumin, with a particular emphasis on its activities at the molecular, cellular, animal, and human levels. A summary of the medicinal chemistry and pharmacology of Curcumin and its derivatives in regard to anticancer activity and their main mechanisms of action is also described in this review.

Keywords: Cancer, Curcumin, Anticancer, Antioxidant, Anti- inflammatory, Medicinal chemistry, Pharmacology.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tanima Debnath Sarkar

Download Article : Click here

News & Updation

  • EJBPS: OCTOBER ISSUE PUBLISHED

    OCTOBER 2021 Issue has been successfully launched on 1 October 2021

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT