Shubham G. Bonde*, Tushar A. Dhote, Ashish L. Pohane and Dr. Sachin J. Dighade


In the pharmaceutical industry Bilayer tablet is the novel technology for the development of controlled release formulation and developing a combination of two or more active pharmaceutical (API) ingredients in a single dosage form. Now a day the use of bilayer tablets has been increased. Bilayer tablet plays an important role for development of controlled release in order to give a successful drug delivery and can be a primary option to avoid chemical incompatibilities between API by physical separation, and to enable the development of different drug release profiles. To reduce capital investment, quite often existing but modified tablet presses are used to develop and produce such tablets. The objective of this review article is to ensure that to reduce the frequency of dosing and drugs are available to its citizen are not only safe and effective, but are also properly manufactured and packaged to meet the established quality target product profile over it shelf life.

Keywords: Bilayer tablets, API, Formulation, Controlled release, frequency of dosing.

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