European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2)

Rajeev K. Jha*, M. Vijayasimha and Gimmi Chhetry

ABSTRACT

Coronavirus disease 2019, (COVID-19) or SARS-CoV-2 is a zoonotic virus causing a combination of severe respiratory diseases. As of May 16, 2020 the continuing COVID-19 became pandemic and spread over 213 countries. Total of 4,675,063 infected patients were reported globally, with 310,291 deaths, and 1,785,231 is recovered. Unfortunately, the global numbers of both infected patients and fatalities will continue to grow in the future months because neither specific and effective antiviral therapies nor vaccine have been identified. India reported, total 85,940 COVID-19 cases (till May 16, 2020), 2,752 people were died and 30,153 people is treated successfully. The fatality rate is expected to 2 to 3%. Diagnosis is by demonstration of the virus in respiratory secretions special molecular tests. Treatment is basically supportive. Prevention is carrying out mainly by home isolation of suspected cases and those with mild illnesses and severe infection. Our study aimed to present an overview of the virus in terms of, transmission, symptoms, Pathophysiology, Diagnosis, treatment, prevention and vaccine.

Keywords: Coronavirus, COVID-19, SARS-CoV-2, ACE2 receptors.