Abstract
IMPLANTATION OF THE TOTAL KNEE ENDOPROSTHESIS IN PATIENT WITH HAEMOPHILLIA B – A CASE REPORT

Omerovi? ?emil*, Tanovi? Edina, Tali? Tanovi? Adnana, Papovi? Adnan, Omerovi? Hana and Rov?anin Emina

ABSTRACT

Inherited bleeding disorders constitute a group of rarely occurring coagulation disturbances caused by deficiency or improper function of blood clotting factors. The clinical course of inherited bleeding disorders is dominated by spontaneous bleeding episodes, leading to irreversible destruction of affected joints. Osteoarthritis is a multi-factorial disease that is the result of mechanical and biological changes in the cartilage and bones beneath the cartilage. Osteoarthritis of the knee is the leading cause of chronic disability in later life. Knee arthropathy is a frequent complication affecting hemophilic patients, which can cause severe pain and disability. When conservative measures fail, total knee arthroplasty may be performed. Total knee arthroplasty is the only way to eliminate the progressive pain and improve the quality of life in end-stage arthropathy of the knee joint. After appropriate medical optimization and with prompt rehabilitation, total knee artrhoplasty can be performed in hemophilic patients with good clinical results and survivor rates comparable to nonhemophilic patients.

Keywords: Hemophilia, knee osteoarthritis, inherited bleeding disorder, total knee arthroplasty.


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