European Journal of Biomedical and Pharmaceutical Sciences

CASE OF YUNIS-VARON SYNDROME

Sudhakar Ajmera and Nagesh Adla*

ABSTRACT

A rare autosomal recessive disorder, Yunis Varon syndrome is reported. A male child had microcephaly, large fontanella with wide sutures, protruding eyes, absent /sparse scalp hair, eyebrows and eye lashes, bilateral absent great toes, and rudimentary thumbs (no phalanges) hypoplasia of bilateral first metatarsal and metacarpals, absent distal phalanx of bilateral toes and fingers. Additional features are micropenis, single palmar crease, with hypo densities involving grey and white matter of bilateral temporo occipital lobes and right partial lobe, and congenital heart disease Atrial septal defect (ostium secundum).

Keywords: Microcephaly, absent great toes and rudimentary thumbs, atrial septal defect, Yunis Varon Syndrome.