European Journal of Biomedical and Pharmaceutical Sciences

STUDY OF RELATIONSHIP BETWEEN ALBUMINURIA AND FUNDUS FINDING OF TYPE 2 DIABETES MELLITUS

*Dr. Ankita Bhattacharya and Dr. Ashok Kumar Maity

ABSTRACT

Background: The prevalence of diabetic retinopathy in general population of India is 3.5% and its ubiquity in population with diabetes mellitus is 18%. At any level of retinopathy, the structure of macula may get altered leading to significant dysfunction due to development of Diabetic Maculopathy. Treatment of established retinopathy can reduce the risk of visual loss by 60%. Once diabetic maculopathy develops, there is no satisfactory treatment and the prognosis is very poor, so it is better to prevent its development. In this study, we have estimated different biochemical parameters of blood in all the participants to evaluate the effect of renal related assays on development and severity of diabetic retinopathy and diabetic maculopathy. Method: Study includes 100 case (diabetic retinopathy) and 100 control( diabetes without retinopathy)subjects. Further, case group was subdivided into subgroups according to its severity and depending on the presence of maculopathy. Thereafter, values of different renal parameters were compared between these sub groups. Result: Renal parameters (Blood Urea, Serum Creatinine) had not shown any statistically significant correlation either with severity of Diabetic retinopathy or CSME patients. Although, raised Urea and Creatinine levels exhibited relevant link with occurrence of DR. However, albuminuria established impressive association with severity of Diabetic retinopathy but not with CSME.

Keywords: Diabetic Retinopathy, Maculopathy, ACR, Diabetic Nephropathy.