European Journal of Biomedical and Pharmaceutical Sciences

MRI EVALUATION OF BONE TUMORS AND TUMORS LIKE CONDITION

*Sapana Koirala, Mukesh Kumar Gupta, Guru Prasad Khanal, Punam Poudyal and Kapil Adhikari

ABSTRACT

Background: MRI plays an important role in diagnosis and treatment of bone tumor in current scenario. MRI can differentiate bone tumor as either benign or malignant and determine its stage thereby helping in making decisions for type/site of biopsy and in planning treatment. Objective: The objectives of our study were to assess the diagnostic accuracy of MRI in bone tumor and tumor like conditions with histopathological correlation and to describe their spectrum and MRI features. Methods: This was a hospital based study carried out on cross sectional basis in the Department of Radiology over a period of one year. 32 patients who underwent MRI and histopathological examination of bone tumor and tumor like conditions were selected for the study. The true positive, false positive, true negative and false negative cases were determined considering histopathology as a gold standard and diagnostic accuracy was calculated. Result: Among 32 patients, 16 (50%) cases were diagnosed as benign tumor, 9 (28%) were diagnosed as tumor like condition, 5 (15.6%) cases were diagnosed as primary malignant tumor and 2 (6.2%) as metastatic tumor. GCT was the most common benign tumor (4,12.5%) and osteosarcoma (3, 9.4%) was the most common malignant tumor. Most cases (29, 90.6%) were accurately diagnosed on MRI and confirmed on histopathology. Diagnostic accuracy of MRI was between 93.7 to 100%. Conclusion: MRI was found to be a valuable modality of imaging in diagnosing various tumor and tumor like conditions of bone.

Keywords: Magnetic Resonance Imaging, Bone tumor and tumor like conditions, Histopathology.