European Journal of Biomedical and Pharmaceutical Sciences

PSEUDOMEMBRANOUS COLITIS

Dr. Madleen Jawad Sobhe Abu Aser*, Dr. Tareq Khaled Aldirdasawi, Dr. Ezzedine Qanoua, Dr. Hamdio Al Turk

ABSTRACT

Pseudomembranous colitis is inflammation of the colon that is most often a manifestation of clostridium difficile infection. That predominantly affects the lower gastrointestinal tract. Its main risk factors are antibiotic use, advanced age, and hospitalization. pseudomembranous colitis, clostridium difficile, antibiotics, pseudomem-branous, fulminant colitis. If laboratory testing and endoscopic finding for clostridium difficile infection are negative, then other less common etiologies should be sought to identify the correct diagnosis. Ischemic colitis, inflammatory bowel disease, medications, chemicals, vasculitis, and multiple infectious pathogens are responsible for non-clostridium difficile pseudomembranous colitis. Exposure history, chronic medical problems, and a current medication list will aid in narrowing the differential diagnosis. Histology varies significantly with underlying etiology and can establish the diagnosis. Treatment is specific to the underlying etiology. The purpose of this research article increase awareness of clinicians and other healthcare professionals about various etiologies of pseudomembranous colitis along with its histological finding and treatment. Our case was admitted from ER a Ten-year-old male patient with chief complaints of cramping left lower abdominal pain, abdominal distension, and loose stools with the passage of blood and pus per rectum, associated with high-grade fever for 10 days.

Keywords: Myoinositol, metformin, polycystic ovarian disease.