Rouholah Fatemi*, Andrew S. Johnson and William Winlow


The novel coronavirus (Covid-19) is spreading rapidly worldwide. According to the World Health Organization, about 5.300 million people have been infected up to now and more than 340000 were died from Covid-19 infection (WHO, 2020). Every day, more and more unknown aspects of this “mysterious virus” are presented to researchers and clinicians. Based on available studies, the main pathology of the disease is that the coronavirus enters the cell by binding to ACE2 receptors and leads to proliferation and destruction of respiratory tract cells and pneumonia (Ge et al., 2013). Findings about the pathology of the disease are low and mostly have been stated based on assumptions. At the beginning of the disease prevalence, it was believed that the virus only involved the respiratory tract, leading to severe pneumonia and hypoxia, and finally death. However, recent reports suggest that in addition to the lungs, other organs, such as the heart, kidneys, eyes, and digestive tract, are also affected (Yuen et al., 2020). These findings have led to a revision of the pathology of the disease, and researchers are investigating new dimensions effects of the virus.

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