European Journal of Biomedical and Pharmaceutical Sciences

CLINICAL PROFILE OF COVID-19 INFECTED PATIENTS ADMITTED IN A TERTIARY CARE HOSPITAL IN NORTHWESTERN ZONE OF INDIA

Dr. Gupta Harsh, Dr. Jangir Ravindra*, Dr. Meena Babulal, Dr. KR Anil, Dr. Ali Imran and Dr. Kumar Surendra

ABSTRACT

The ongoing COVID-19 pandemic, which started as series of unexplained pneumonitis in Wuhan, China has soon pushed the world in the abyss. It has caused huge loss in terms of life and property. India with more than billion population is becoming the new hotbed of the infection. This study was undertaken to evaluate the clinical profile, socio-demographic distribution, risk factors and compli- cations in COVID-19 positive patients in Northwestern Rajasthan. This is a cross-sectional study, done at the Department of medicine SP Medical College, Bikaner, Rajasthan. 129 COVID-19 posi- tive patients were part of the study out of which 75 (58.13%) were male. The average age was only 34.7 years. The mean duration of stay was 9.5 days and was significantly more in patients with co- morbidities. Initial group of patients had only travel history, but later the majority of patients had contact history with COVID-19 positive case. 89 (68.9%) patients were completely asymptomatic and out of 40 symptomatic patients, fever was the commonest symptom (72.5%) followed by cough (67.5%) and breathlessness (30%). 21 patients (16.2%) had co-morbidities most common being Type 2 Diabetes and Hypertension. Out of 7 patients who died, 6 had one or multiple co-morbidi- ties. X-ray changes were present in only 6.2% patients. The mean CBC parameters were normal. Leucocytosis and granulocytosis was associated with more ICU admission and adverse outcome. Mean SGOT and SGPT were deranged. The relationship between NLR and severity of disease was found to be statistically significant. The early diagnosis of COVID-19 cases and early prediction of adverse outcome will help physicians to optimally utilise the limited resources.

Keywords: Leucocytosis and granulocytosis.