SEASONAL EFFECT ON IN VITRO ALPHA AMYLASE INHIBITORY ACTIVITY OF ABUTILON INDICUM LEAVES
Tanaya Ghosh and Prasanta Kumar Mitra*
ABSTRACT
Abutilon indicum Linn. ( A. indicum L.) is a medicinal plant being used in traditional medicine since long.
Recently we have confirmed in vitro alpha amylase inhibitory activity of A. indicum L. leaves. As
pharmacological activities of medicinal plants vary with season, aim of the present work was to see the seasonal
effect on in vitro alpha amylase inhibitory activity of A. indicum L. leaves, if any. Leaves of A. indicum L. were
collected in winter, summer, autumn and rainy seasons from medicinal plant garden of the North Bengal
University and authenticated by the taxonomist. Leaves were extracted with ethanol and the extract was checked
for in vitro alpha amylase inhibitory activity by the standard method. Acarbose, a standard alpha amylase
inhibitor, was used as control. Results showed that A. indicum L. leaves of rainy season (June – August) had
maximum alpha amylase inhibitory activity. Result was comparable to that of acarbose. Leaves of A. indicum L.
of rainy season may therefore be utilized to keep post prandial blood sugar of the diabetic patient under control
and thereby used in the treatment of diabetes.
Keywords: Abutilon indicum Linn. Leaves, alpha amylase inhibitory activity, seasonal variation, acarbose, diabetes.
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