Abstract
A REVIEW ON BIODEGRADABLE POLYMERS USED IN PHARMACEUTICAL NANO FORMULATIONS

*Sanat Kumar Dash, N. Khirod Kumar, Partha Sarathi Das and Ch. Niranjan Patra

ABSTRACT

Biodegradable polymers have been used frequently as drug delivery vehicles owing to its ability to increase bioavailability, better encapsulation, control release and less toxic properties. The biodegradable polymers will slowly replace the use of existing non-biodegradable polymers in formulations because their distinct advantages. Use of biodegradable polymers in nanoparticulate drug delivery systems will also reduce the drug dosage frequency and will increase the patient compliance. In near future these systems can be used for exploiting many biological drugs which have poor aqueous solubility, permeability and less bioavailability. Various biodegradable polymers such as Polylactic acid (PLA), Poly (lactic-co-glycolic acid) (PLGA), Gelatin, chitosan, polyacrylamide, polycapro lactone were reviewed extensively for their different applications in drug delivery systems.

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