European Journal of Biomedical and Pharmaceutical Sciences

CARCINOSARCOMA OF LARYNX: A RARE CASE WITH EXCELLENT OUTCOME WITH STANDARD TREATMENT

Abhishek Soni,* Meenakshi Sharma, Renuka Verma, Vivek Kaushal

ABSTRACT

We report a case of a 60-year-old previously healthy male with carcinosarcoma of larynx who presented with hoarseness of voice. Carcinosarcoma carcinoma mimics sarcoma and carcinoma in histopathological parameters and it is difficult to categorize the histopathological type of sarcoma which is usually supplemented by immunohistochemistry for various markers. Carcinosarcoma of larynx is an uncommon presentation. The standard treatment is surgery and/or adjuvant radical external beam radiotherapy with standard fractionation schedule. Surgery is usually done in early lesions and reserved for advanced lesions. Advamced lesions are treated by radiotherapy alone as primary treatment. The prognosis of carcinosarcoma of larynx is felt to be extremely poor with high recurrence rate. Contrary to it, this case demonstrates that a good response with standard therapy is possible.

Keywords: Carcinosarcoma, surgery, radiotherapy, larynx.