European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON PRESCRIBING PATTERN AND PHARMACOECONOMICS OF ANTIBIOTIC USE IN A TERTIARY CARE HOSPITAL

Dr. Beulah Milton, *Jerry Kharngi, Dipankar Debnath, Soumyadeep Debnath

ABSTRACT

Introduction: There are various antibiotics available in the market with different brand names with respect to their generics. Due to the complexity of treatment in individual patients, this study has been used to assess the most commonly prescribed antibiotics in various age groups and their various dosage forms and also to evaluate the cost of anti-microbial regimen. Objectives: The Primary objective is to evaluate drug use pattern and pharmacoeconomics of antibiotics in a tertiary hospital. The Secondary objectives are to assess the rationality of prescribing pattern, to compare the percentage of the antibiotics prescribed in generic and brand and to carry out the cost identification analysis of antibiotics used in the in-patients. Methodology: This observational study was carried out in the various in-patient departments of the Sapthagiri tertiary care Hospital. The study was carried out for 110 patients satisfying the inclusion and the exclusion criteria in a 6 months period. The source of the data in this study are Patients’medicationchart and data is collected by using a self-designed data collection form. Results: The class of antibiotics which was used maximum was found to be Cephalosporins and class of antibiotics which was used minimum was found to be carbapenem. For 110 patients, the total number of antibiotics were prescribed to be 213, out of which fixed dose combinations used were 14.08% and individual antibiotics used were 85.90%, 23% antibiotics were prescribed as generic and 77% antibiotics were prescribed as brand. Average number of Antibiotics per Prescription was 1.9, average cost of Antibiotics per prescription was found to be 2149.35, average cost of Antibiotics per prescription if all the antibiotics were to be prescribed in Generic is 616.15. Conclusion: Hence it is very important to monitor the prescribing pattern of antibiotics and also the cost per prescription associated with the antibiotic therapy which can prove to be a valuable information to prescribers for rationality.

Keywords: Pharmacoeconomics, Antibiotics, Generic, Brand.