Abstract
PREVALENCE OF CANDIDA ISOLATES FROM WOMENS AFFECTED WITH URINARY TRACT INFECTIONS AT A TERTIARY CARE HOSPITAL

Dr. Neelam Chauhan, Dr. Sheetal Sharma* and Dr. Vipin Kathuria

ABSTRACT

An increase in the incidence of Urinary tract infections due to Candida species has been observed. The higher rate of Candiduria due to Non albicans Candida is now being reported than due to Candida albicans. The emergence of drug resistance in Candida species has complicated the patient management. The aim of this study was to observe the prevalence of Candida species in UTIs and their antifungal susceptibility pattern in a tertiary care hospital. An observational study was conducted for a period of six months in Pacific Medical University, Udaipur. A total 75 clinical specimens collected from women with Urinary Tract Infection (UTI). Among the 75 samples analysed, 41 were positive for Candida. The Candida isolates was recorded higher in urine specimen (55.5%), followed by vaginal swab (53.3%). The isolation and identification of Candida isolates were done by the study of its morphological, cultural and biochemical characteristics. The phenotypic results showed that Candida albicans (68.2%) was the predominant species followed by C. glabarata (24.3%) and C. krusei (07.3%). The antibiotic susceptibility study revealed that all the species of Candida isolates were 100% susceptible to Amphotericin B and Nystatin whereas Ketoconazole was evaluated with low susceptibility.

Keywords: Candida, Antifungal, Urinary Tract Infection.


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