European Journal of Biomedical and Pharmaceutical Sciences

STUDY TO ASSESS RESISTANT HYPERTENSION, IT’S PREVALENCE AND COMPLICATIONS IN PATIENTS REPORTING TO TERTIARY CARE CENTER

Dr. Iqra Mustafa*, Dr. Ali Sibtain Azhar, Dr. Muhammad Zaid Bin Zia

ABSTRACT

Objective: To study the incidence, prevalence, and complications of resistant hypertension among people of varying age groups in public hospital of Pakistan. Materials and method: A cross sectional study was conducted at the department of medicine in Jinnah Hospital Lahore from February 2019 to July 2019. A total of 120 patients were studied. The number of female patients were 43 and the number of male patients were 77. The patients were diagnosed as resistant hypertensive if they showed blood pressure measurements of 140/90 mm Hg or more than that in office setting and out office settings, and showed suboptimal response to three antihypertensive drugs, one of which was, by preference, a diuretic. White coat effect and inadequate adherence to regimen, which could produce profound pseudo resistance, were eliminated before diagnosing the patients with resistant hypertension. Result: A total of 120 patients were studied and their ages varied up to 20 – 80 years with a mean age of 52.37 years ±6.92 years. The number of female patients were 43 (35.8%) and number of male patients were 77 (64.1%). The BMI of patients happened to be in a range of 19 – 32 Kg/m², with a mean BMI 26.59 Kg/m² (±3.28) Patients were further divided into two subgroups of age (20 – 50 years and 50 – 80 years). The findings of study showed a higher incidence of resistant hypertension among female patients (48.8%) and age group of 50 – 80 years was found to be more at risk (28.7%). Conclusion: The study showed higher prevalence of resistant hypertension among females in comparison to male hypertensive patients. The age group of 50 – 80 years was found to be more affected.

Keywords: Resistant hypertension, Obesity, White coat effect, Pseudo resistance.