Abstract
CLINICAL FEATURES AND EPIDEMIOLOGICAL CHARACTERIZATION OF PANDEMIC INFLUENZA A/H1N1PDM09 IN CÔTE D'IVOIRE

Konan Kouassi Yannick*, Kadjo Adjé Hervé Albéric Junior, Kouassi Konan Adjoua Rose Marie Clémence, Kouakou Bertin, DOSSO Brétin-Mireille and N’Guetta Assanvo Simon-Pierre

ABSTRACT

Background: Pandemic influenza A/H1N1Pdm09 viruses are among the most diagnosed and isolated influenza viruses worldwide. Their movement is widely documented but factors influencing this movement still poorly described. Côte d'Ivoire is at risk of influenza epidemics because of the precarious of he’s health system and the poverty of he’s population. The objective of this study is to describe the demographic factors and the characteristics of the risk factors associated with the movement of pandemic influenza A/H1N1Pdm09 in Côte d'Ivoire. Methods: Diagnosis of A/H1N1Pdm09 was performed by polymerase chain reaction targeting the hemagglutinin (HA) gene using SuperScript III Platinum® One-Step qRT-PCR System Amplification Kit (Invitrogen, USA) and primer Fw: AACTACTACTGGACTCTRCTKGAA, Rw: CCATTGGTGCATTTGAGKTGATG and probe : FAM-TGAYCCAAAGCCTCTACTCAGTGCGAAAGC-BHQ-1. RT-PCR was performed on 16,348 nasopharyngeal specimens collected from 2010 to 2017. Samples were collected from nine monitoring sites. Microsoft Excel and R 3.0.1 software were used for data analysis. Results: A proportion of 9.16 % of 16,348 samples tested were positive for influenza A over the entire study period and 57.41 % were A/H1N1Pdm09. A/H1N1Pdm09 was significantly distributed over the entire study period, within years and over all seasons. The average age of persons with A/H1N1Pdm09 was 12.47 and the most infected age group was 6 to 15, who were 3.04 times more likely to be infected than persons over 65 years of age. Malnutrition is the risk factor most associated with A/H1N1Pdm09 infections at a rate of 34.38%. Conclusion: Epidemiology of pandemic influenza in Côte d'Ivoire is characterized by an almost continuous movement of these viruses. It has a more pronounced impact among people aged 6 to 15 years and is a major health problem for those suffering from malnutrition and chronic pneumonia.

Keywords: Influenza A/H1N1Pdm09, Demographic characterization, risk factor, Côte d'Ivoire.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW NOVEMBER ISSUE PUBLISHED

    NOVEMBER 2020 Issue has been successfully launched on 1 November 2020.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT