European Journal of Biomedical and Pharmaceutical Sciences

DETERMINATION OF PROTEIN C LEVEL IN CORONARY HEART DISEASE IN SUDAN

Alaa Mohamed A. Alnoor* and Mahdi H. A. Abdalla

ABSTRACT

Introduction: Coronary Artery disease is a leading cause of morbidity and mortality in the developed and developing countries. Several underlying genetic and environmental factors have been implicated in its etiology. Some of the coagulation risk factors implicated in the development of coronary heart disease include protein C. Material and method: in the present study we determined the plasma level of Protein C level by ELIZA methods. A total of 90 samples were collected (45 with Coronary Artery Disease Patients and 45 healthy controls), the mean of Protein C level among case group (62.1±9.1) was significantly lower than control group (121.2±20.0), (p. Value 0.000). Results: Data were analyzed using statistical package for the social science (SPSS) version 22. There was significantly lower in PC in Coronary artery patients when compared to control group. Conclusion: The Protein C level results where is significantly Lower in case than control correlate (p.value:0.000).

Keywords: Coronary Artery Disease, Protein C, Sudan, 2020.