PHARMACOKINETIC AND PHARMACODYNAMICS PERSPECTIVES OF PANCHKARMA W.S.R. TO THERAPIES INVOLVING ORAL AND NASAL ROUTE FOR DRUG ADMINISTRATION
Dr. Abhishek Shipte* and Dr. Amit Mukherjee
ABSTRACT
Ayurveda the medical stream of classical Indian science elaborated various therapeutic and preventive approaches for the restoring of normal health condition. In this regard Ayurveda described some detoxification techniques also for preventing and curing various health ailments. Panchkarma is one such purifications method of Ayurveda which provides significant health benefits in many pathological conditions and also prevent invasion of disease causative factors. Vamana, Virechana, Basti, Nasya & Raktamoksha are some approaches of Panchkarma which performed for specific health benefits. Panchkarma facilitates transportation of drugs utilized in therapy and also boost normal physiological functioning of body. Each Panchkarma procedures acts through their own mechanism therefore it is prerequisite to understand pharmacokinetic and pharmacodynamics perspectives of Panchkarma therapy. Thus present article explored pharmacokinetic and pharmacodynamics considerations of some of the modalities of Panchkarma. It is expected that this article will help upcoming researchers of field to understand mode of action of therapy in better way.
Keywords: Ayurveda, Panchkarma, Pharmacokinetic, Pharmacodynamics.
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