SEROPREVALENCE OF TOXOPLASMA IG G IN NORMAL POPULATION OF CALICUT, KERALA
*Sheela Mathew and Aaron George John
ABSTRACT
Infection with Toxoplasma Gondii can cause severe illness when contracted congenitally or when reactivated in immune suppressed persons. Different studies are reporting varying geographical prevalence. The geographical prevalence is unknown in Kerala. This study was conducted to determine the prevalence of Toxoplasma Gondii in a representative sample of adult population of North Kerala. This was a prospective observational study, conducted in the community. Sera collected from 250 healthy adults and an IgG antibody was detected by ELISA method. The sample population was not suffering from any disease and there was no past history of any blood transfusion. They belonged to both rural and urban areas, and having different occupations. Out of 250 samples 68 showed value >15.95 iu/ml which is mentioned as upper limit of normal (27.2%). Among the positive cases there were 59% males and 41% females, age varied from 20-70.There was no evidence of rising antibody titer in parallel with rising age. Since the prevalence is high, two vulnerable groups namely pregnant ladies and immune suppressed population should be given proper health education to minimize chance of infection.
Keywords: Toxoplasmosis, Toxoplasma IgG, Seroprevalence, North Kerala.
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