European Journal of Biomedical and Pharmaceutical Sciences

HISTOPATHOLOGICAL FINDINGS IN SALIVARY GLAND SPECIMENS AT KHMC. A RETROSPECTIVE DESCRIPTIVE ANALYSIS OVER A PERIOD OF SIX YEARS

Lina A. Al-Nahar. MD. FRCPath*, Zaid El Omari. MD, Elham M. Alsharaiah. MD, Ahmed A. Bawaneh. MD, Majdi A. Al Soudi. MD and Manar S. Alafeshat. MS.

ABSTRACT

Aim: The aim of this study is to review the histopathological reports of salivary gland specimens and to describe their main pathological findings. Materials & Methods: We collected data from 143 patients who underwent excisional or incisional biopsies from salivary glands at the King Hussein Medical Centre (KHMC) / Princess Iman Laboratory& Research Centre over a six-year period from January 2013 to December 2018. Results: Patients had a wide age range (from 5 years to 90 years), with a male to female ratio of 0.9:1. The pathological findings varied from neoplastic (55 cases) to non-neoplastic lesions (88 cases). The neoplasms included benign (36/55) and malignant (19/55) tumours. The non-neoplastic lesions included benign cysts (5/88), autoimmune sialadenitis (22/88) and chronic sialadenitis/sialolithiasis (61/88). Conclusions: Salivary glands are one of the major structures in the maxillofacial region. Biopsies of salivary glands may reveal a wide range of pathological findings, and there are different methods of medical and surgical treatment of salivary gland disease. Histopathological assessment is crucial in determining the modality of treatment for patients.

Keywords: Salivary gland, Histopathology, Neoplasms, Sialadenitis.