European Journal of Biomedical and Pharmaceutical Sciences

ASSOCIATION OF SERUM OMENTIN-1 AND LEPTIN WITH ACUTE MYOCARDIAL INFARCTION

*Hira Tanvir, Taha Masood and Fatima Zain

ABSTRACT

Introduction: Obesity, the most common nutritional disorder in industrialized countries, is associated with an increased mortality and morbidity of cardiovascular disease (CVD). Objectives: The main objective of the study is to find the association of serum Omentin-1 and Leptin with acute myocardial infarction. Material and methods: The data was collected from Doctors Hospital and Research Center, Lahore during January 2020 till June 2020. The data was collected after the permission of ethical committee of hospital. The data was collected from patients who suffering from acute myocardial infarction and visited OPD of the hospital regularly. The general information of the patients include age, BMI, BP, hypertension, smoking and previous history of myocardial infarction. Results: The data was collected from 50 patients. The mean age of the patients was 26 ± 3.9 years, with a maximum number of patients (60.2%) being within the age of 25-30 years and the rest in the age group of 20-25 years. The youngest patient was 20.1 years old. AMI in very young patients was highly prevalent in urban population (63.9%). Conclusion: It is concluded that Serum Omentin levels were significantly lowered while no change was found in serum leptin levels. Serum omentin-1 levels were independently associated with the MI.

Keywords: CVD, BMI, BP, MI.