European Journal of Biomedical and Pharmaceutical Sciences

MEDICATED CHEWING GUM: WONDER THERAPY

Dr. Geeta Bhagwat*, Adnan Siddique, Aqsa Siddique, Salman Shaikh, Deepak Yadav and Laxmi Prajapati

ABSTRACT

Medicated chewing gum are the novel oral drug delivery system which can be use for both local and systemic action. MCG are the solid single dose preparation which are intended to be chew and they are not supposed to be swallowed thus this type of drug delivery system provide prompt termination of therapy at anytime which provide a very distinct advantage over other oral novel drug delivery system. MCG provide high degree of patient compliance as it is easy for administration without water it is found. Now a days medicated chewing gum therapy are more seen as the prophylaxis therapy and there is large market of medicated chewing gum which are used for oral health like fluorides containing chewing gum for dental caries, aspirin containing for analgesic etc. Medicated chewing gums contain a gum base which is a heart of the preparation which provide the chewing gum its chewing consistency and other desired properties like strength, texture, surface, plasticity. apart from gum base it contain other supporting ingredients which enhances the look and appearance of chewing gum and make it market ready like flavourant, colourant, sweetener. the present review article will enlighten everyone with nicely discussed advantages and disadvantages, composition, manufacturing method, factor affecting release of active ingredients, evaluation and quality control parameter, application, future trend of medicated chewing gum.

Keywords: Chewing gum, Prophylaxis therapy, Dental caries, Gum base.