Abstract
DEVELOPMENT AND EVALUATION OF MEDICATED CHEWING GUM CONTAINING ONDANSETRON HYDROCHLORIDE

Suraj Yadav*, Sandeep Atram, S. D. Pande and Nishan N. Bobade

ABSTRACT

Chewing Gums are mobile Drug Delivery Systems, with a potential for administering drugs either for local or systemic absorption via buccal route. It can be administered discreetly without water. Medicated Chewing Gums contains gum base along with Antiemetic agent which is intended to chew not to be swallowed. Also this formulation contains Polyisobutylene, Soya lecithin, Calcium Carbonate and Flavoring agents. The Medicated Chewing Gums were prepared by the direct compression method. The prepared formulations were evaluated for various pre-compression and post compression parameters. The in-vitro drug release of Formulation MCG3 showed satisfactory drug release within 30 min. at various chewing conditions. From the results it is concluded that the Chewing Gum Containing Ondansetran HCl will be the potential dosage form for the treatment of chemotherapy induced nausea and vomiting.

Keywords: Medicated Chewing Gum, Ondansetron Hydrochloride, Buccal Route, Nausea And Vomiting.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • EJBPS: JANUARY ISSUE PUBLISHED

    JANUARY 2020 Issue has been successfully launched on 1 January 2020.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT