European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF SERUM ELECTROLYTES LEVEL IN HYPOTHYROID PATIENTS

Alok Kumar Maurya, Anil Kumar*, Hare Krishna Sharma, Anoop Kumar and Sushil Yadav

ABSTRACT

Introduction- Hypothyroidism and hyperthyroidism are common disorders of thyroid dysfunction due to decrease or increase of thyroid hormone level. Different electrolyte disorders in association with thyroid dysfunction were observed in the literature. Hence hypothyroidism seems to affect different electrolyte metabolism however these relationships require further investigations and need to be confirmed in more patients. Therefore, present study was directed to estimate serum electrolytes (sodium potassium calcium phosphorus and magnesium) levels in hypothyroid patients. Aim- To evaluate serum electrolytes level in hypothyroid patients. Objectives- To estimate serum electrolytes (Sodium, Potassium, Calcium, Magnesium and Phosphorus) level in hypothyroid patients and compare in different age groups. To find out correlation of serum TSH with serum electrolytes (sodium, potassium, calcium, phosphorus and magnesium) respectively among hypothyroid patients. Material & Method- The present study was conducted on male & female patients (age group 20-50 years) diagnosed with hypothyroidism, attending the OPD and IPD of general medicine Teerthanker Mahaveer Hospital. The study group was comprised in different age groups of 60 primary hypothyroid patients. Result- A significant increase in serum TSH and Sodium is observed in cases when compared to controls (p<0.001). A significant decrease in serum Potassium is observed in cases when compared to controls (p<0.001). A statistically non significant increase in serum Calcium and Magnesium is observed in cases when compared to controls (p>0.001) and A significant increase in serum Phosphorous is observed in cases when compared to controls (p<0.005). A positive correlation was observed between serum TSH with serum Sodium, Phosphorous and negative correlation was observed in serum Potassium, Phosphorous but strong negative correlation was observed in serum Calcium. Conclusion- The present study indicated that hypothyroid patients to be repeatedly checked for disturbances in serum electrolytes and electrolyte profile should be checked regularly, along with thyroid profile. Early finding and treatment should be provided in the form of dietary supplementation so as to check further complications related with electrolytes.

Keywords: Sodium, Potassium, Calcium, Magnesium, Phosphorous, Thyroid Stimulating Hormones (TSH).